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NEWMEDS - The research leading to these results has received support from the Innovative Medicine Initiative Joint Undertaking under grant agreement n° 115008 of which resources are composed of EFPIA in-kind contribution and financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013).
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Title: Fenfluramine-Induced Serotonin Release Decreases [11C]AZ10419369 Binding to 5-HT1B-Receptors in the Primate Brain
Author: S.J. Finnema, A. Varrone, T.J. Hwang, B. Gulyás, M.E. Pierson, C. Halldin, and L. Farde
Journal: Synapse
Link: Synapse_Link
Title: Activation of thalamocortical networks by the NMDA receptor antagonist phencyclidine. Reversal by clozapine.
Author: Noemí Santana, Eva Troyano, Guadalupe Mengod, Pau Celada, and Francesc Artigas
Journal: Biological Psychiatry
Link: Biological_Psychiatry_Link
Title: Role of thalamic projection in NMDA receptor-induced disruption of cortical slow oscillation and short-term plasticity
Author: Tamás Kiss, William E. Hoffmann, Liam Scott, Thomas T. Kawabe, Anthony J. Milici, Erik A. Nilsen and Mihály Hajós
Journal: Frontiers in Psychiatry
Link: Frontiers_in_Psychiatry_Link
Title: A within-subject cognitive battery in the rat: differential effects of NMDA receptor antagonists
Author: Sophie Dix, Gary Gilmour, Slavinka Potts, Janice W. Smith, Mark Tricklebank
Journal: Psychopharmacology
Link: Psychopharmacology_Link
Title: A comparison of the effects of ketamine and phencyclidine with other antagonists of the NMDA receptor in rodent assays of attention and working memory
Author: Smith, Janice et al.
Journal: Psychopharmacology
Link: Psychopharmacology_Link
Title: Maternally Derived Microduplications at 15q11-q13: Implication of Imprinted Genes in Psychotic Illness
Author: Ingason, Andrés et al.
Journal: AJP
Link: AJP_Link
Title: 5-HT1A Receptor Agonists Enhance Pyramidal Cell Firing in Prefrontal Cortex Through a Preferential Action on GABA Interneurons
Author: Laia Llado-Pelfort, Noemí Santana, Valentina Ghisi, Francesc Artigas, and PauCelada
Journal: Cerebral Cortex
Link: Cerebral_Cortex_Link
Title: New translational assays for preclinical modelling of cognition in schizophrenia: The touch screen testing method for mice and rats
Author: Bussey, T. J. et al
Journal: Neuropharmacology
Link: PubMed_Link
Title: Clozapine Reverses Phencyclidine-Induced Desynchronization of Prefrontal Cortex through a 5-HT1A Receptor-Dependent Mechanism
Author: Lucila Kargieman, Maurizio S Riga, Francesc Artigas and Pau Celada
Journal: Neuropsychopharmacology
Link: Neuropsychopharmacology_Link
Title: Confirmation of fenfluramine effect on 5-HT1B receptor binding of [11C]AZ10419369 using an equilibrium approach
Author:Sjoerd J Finnema, Andrea Varrone, Tzung-Jeng Hwang, ChristerHalldin and Lars Farde
Journal: Journal of Cerebral Blood Flow & Metabolism
Link: Cerebral_Blood_Flow_Link
Title: Delta oscillation and short-term plasticity in the rat medial prefrontal cortex: modelling NMDA hypofunction of schizophrenia
Author: Kiss T, Hoffmann WE, Hajós M
Journal: The International Journal of Neuropsychopharmacology
Link: Neuropsychopharmacology_Link
Title: The pharmacological sensitivity of a touchscreen-based visual discrimination task in the rat using simple and perceptually challenging stimuli
Author: J.C.Talpos, A.C.Fletcher, C.Circelli, M.D.Tricklebank and S.L.Dix
Journal: Psychopharmacology
Link: PubMed_Link
Title: Spontaneous object recognition and its relevance to schizophrenia: a review of findings from pharmacological, genetic, lesion and developmental rodent models
Author: L.Lyon, L.M.Saksida and T.J.Bussey
Journal: Psychopharmacology
Link: PubMed_Link
Title: Biomarkers predicting treatment outcome in depression: what is clinically significant?
Author: Rudolf Uher, Katherine E Tansey, Karim Malki and Roy H Perlis
Journal: Pharmacogenomics
Link: PubMed_Link
Title: NMDA receptors, cognition and schizophrenia - Testing the validity of the NMDA receptor hypofunction hypothesis
Author: Gary Gilmour, Sophie Dix, Laetitia Fellini, Francois Gastambide, Niels Plath, Thomas Steckler, John Talpos, Mark Tricklebank
Journal: Neuropharmacology
Link: PubMed_Link
Title: Translating cognition from animals to humans
Author: J.F. Keelera, T.W.Robbins
Journal: Biochemical Pharmacology
Link: PubMed_Link